ToolGen

Services

Empowering research and industrial projects through custom gene-editing and technical services.

Overview

Advantages of ToolGen's Genome Edited Cell Line Production Service

Customized Production

  • Optimized sgRNA selection and cell line engineering through pre-consultation to meet the client’s specific objectives.
  • Provides tailored strategies for cell lines that are difficult to edit, ensuring successful genome modification

High-Efficiency Editing

  • Mixed Cell Pool Service: Provides pools with up to 60% In/Del efficiency.
  • Single Cell Clone Service: Enables selection of clones with 100% In/Del efficiency.
  • Utilizes highly specific sgRNA and transfection with Cas9 protein (RNP) or mRNA to minimize off-target effects.

Various Applications

  • Gene function research
  • Customized disease model cell production
  • Cell and gene therapy research and development

The Strengths of ToolGen IVT Service

  • IVT is performed using the DNA template provided by the customer
  • Depending on the research objectives, a highly stable modified mRNA (5moU) option is available
  • Production can be scaled to meet your needs

Workflow

This service is exclusively for cell lines that have been confirmed to be Mycoplasma-free.

Service

Single Guide RNA (sgRNA) Synthesis

Contact Information

Research Planning

ChoSungHee, Senior Researcher

E-mail: services@toolgen.com

Tel: +82 2 3660-1320